ISTT Survey on Production of Transgenic Mice has been closed

ISTT Survey on Production of Transgenic Mice has been closed
ISTT Survey on Production of Transgenic Mice has been closed

The ISTT Survey on Production of Transgenic Mice was closed on September 30th, 2009. We will now process all raw microinjection data collected and will try making the best use of them, with the help of our associated statistician Laura Barrios, from CSIC.

We have managed to collect: 85 facilities registered, 66 facilities submitted data, 86 sets of data submitted. This is not close to 100 facilities submitting data, as we aimed for, but still a respectable number of facilities that, hopefully, will be enough to extract all sources of variability and generate a number of interesting conclusions, trends and suggestions that could be of help to all submitters and, also, to anyone interested in generating transgenic mice.

Thanks to all of you that contributed with your raw microinjection data. As indicated, all submitters will be contacted, independently, with a customized analysis of their data. Tom Fielder has been invited to present the outcome of these analyses in Berlin, at the next TT2010 meeting. Therefore, don’t miss his talk and do register to attend the next Transgenic Technology meeting!

ISTT Survey on Production of Transgenic Mouse closing on September 30

ISTT Survey on Production of Transgenic Mice by DNA microinjection
ISTT Survey on Production of Transgenic Mice by DNA microinjection

All good things must come to an end, and our survey of DNA microinjection data is no exception. In order to allow us to process everyone’s files and perform individual and global analyses in time to make a full report at the TT2010 meeting (March 22-24, 2010, Berlin), we have decided we must close the survey at the end of this month. Therefore, September 30, 2009 will be the last day you will be able to submit your data.

If you have not done so already, please go to the survey website, read the instructions carefully, and submit your facility description and microinjection data. Remember, all submissions will be treated with the utmost confidentiality, and you will receive a custom analysis of your data, in addition to the overall results.

If you would like to join us at the TT2010 meeting and hear firsthand about the results, please visit: http://www.tt2010.org

ISTT Survey on Production of Transgenic Mice

At the TT2008 meeting, Tom Fielder (Univ. California-Irvine, USA) presented the ISTT Survey on Production of Transgenic Mice Production. This is a survey of transgenic mouse core facilities, conducted by the International Society for Transgenic Technologies (ISTT), for the purpose of establishing performance standards. The first part of this survey will focus on DNA microinjection.

Our goal is to obtain data from at least 100 different facilities world-wide. The more facilities that participate, the more reliable the results will be. All facilities will benefit from having officially recognized standards for such measures as embryo and pup yields, rates of transgenesis, etc., as well as the expected variability in such measures. Established facilities will be able to refer to independent standards in dealing with dissatisfied clients, and new facilities will be able to aim for an achievable goal. We may even be able to discover an optimum combination of factors that will allow every facility to improve.

Please, visit the WEB site of the ISTT Survey on Production of Transgenic Mice for additional information and for contributing your microinjection data. Thanks for your collaboration!.