The ISTT is proud to announce the winners of the TT2106 ISTT Registration Awards and the ISTT & Genentech Travel Awards.
This year, the ISTT Board of Directors has awarded 12 ISTT members an ISTT Registration Award, which will cover their registration fee for TT2016.
Denise Grant Lanza
The ISTT and Genentech have also awarded 2 of the successful applicants an additional travel award. The awardees are: Melissa Larson from the University of Kansas Medical Center, Kansas City, Missouri, USA and Sara Ortica Gatti from the Paris-Saclay Institute of Neuroscience, Paris, France. Their award includes airfare to and accommodation at TT2016. Both travel award winners will be presenting their work at the meeting.
Post prepared and submitted by Elizabeth Williams on behalf of the ISTT Board of Directors.
A minimum of six Registration Awards will be sponsored by the International Society for Transgenic Technologies for ISTT members wishing to attend the 13th Transgenic Technologies (TT2016) meeting in Prague, The Czech Republic, on 20-23rd March, 2016. Selected applicants will be awarded funding to cover registration fees plus attendance at all social events. However, the award does not cover travel expenses, hotel accommodation or attendance at pre-meeting events.
Applicants who are not yet members of the ISTT may join the ISTT and simultaneously submit their Registration Award application. Only those applications from members who have paid their current annual fees will be considered.
Applicants must register first at the TT2016 Meeting website and select, as a payment method, “Application for Registration Awards” as a payment method. The ISTT will pay the Registration Fee of all applicants selected for an award. Applicants not selected will be kindly requested to pay the corresponding registration fee.
Applications and additional required documents (see below) should be sent, along with the meeting registration confirmation, to the official ISTT email address, email@example.com, by 30th November, 2015.
Additional Documentation Required
a) Applicant’s CV
b) For ordinary members, a letter from the applicant describing how he/she will benefit from attending the TT meeting
c) For technician/student members, a letter of support from the applicant’s PI or supervisor stating how attendance will benefit the applicant’s career
ISTT Registration awards will be selected by a subset of ISTT Council members, with preference given to:
1) Student/Technician ISTT Members
2) ISTT Members submitting an abstract for presentation as a poster/short-oral communication at the TT meeting
3) Any other ISTT Member
Awards to the selected applicants will be announced by December 15th, 2015 and awardees will receive a diploma marking the event at the end of the TT2016 Meeting.
The aim is to offer a training course of excellence for researchers and technicians working in animal transgenic field. The topics will be focused on both the basic knowledge and the latest advances in transgenic technologies. The course consists of a 1st week of lectures sessions and a 2nd week of practical sessions. In addition, a mini symposium (11-12 September) is organized in order to extend the impact of the presence of the professors to other researchers, technicians and posgraduate students. Current programs for the COURSE and MINI-SYMPOSIUM.
Confirmed speakers attending this Course and mini-Symposium include:
Michel Cohen-Tannoudji, IPParis, France
Francina Langa, IP Paris, France, ISTT member
Ignacio Anegón, INSERM, Nantes, France, ISTT member
Lluis Montoliu, CNB, Spain, ISTT member
Jorge Sztein, consultant, Spain
Sylva Haralambous, HPI, Greece, ISTT member
Naomi Nakagata, CARD, Kumamoto U, Japan, ISTT member
Charles Long, Texas A&M University, USA
Daniel Salamone, Fagro, UBA, Argentina
Adrian Mutto, UNSM, Argentina
Marcelo Rubinstein, INGEBI, Argentina, ISTT member
Marcelo Bertolini, UNIFOR, Brazil
Local professors and instructors include:
Magdalena Cárdenas, IP Montevideo, Uruguay
Ana Paula Mulet, IP Montevideo, Uruguay
Geraldine Schlapp, IP Montevideo, Uruguay, ISTT member
María Noel Meikle, IP Montevideo, Uruguay, ISTT member
Gabriel Fernández, IP Montevideo, Uruguay
Ana Paula Arévalo, IP Montevideo, Uruguay
Martina Crispo, IP Montevideo, Uruguay, ISTT member
Pedro C. dos Santos, IRAUy, Uruguay
Natalibeth Barrera, IRAUy, Uruguay
Federico Cuadro, IRAUy, Uruguay
Alejo Menchaca, IRAUy, Montevideo, Uruguay, ISTT member
People interested in participating in this COURSE must send the COURSE Application Form to firstname.lastname@example.org
A maximum of 20 students will be accepted for the COURSE taking into account personal qualifications. There is no registration fee for the COURSE. Support for accommodation, per diem and local transportation will be provided to all participants from abroad. Travel expenses are not included.
People interested in participating in the MINI SYMPOSIUM must send the SYMPOSIUM Registration Form to email@example.com
SYMPOSIUM fee is U$S 100.
SAVE THE DATES!
Deadline for COURSE applications is June 28th
Deadline for SYMPOSIUM registrations is July 19th
For any further information contact: firstname.lastname@example.org
About a month ago, shortly before the season break, and very timely to enjoy its Christmas Market (Weihnachtsmarkt), the kick-off meeting of the Project SALAAM (Sharing Advances on Large Animal Models) took place in Munich (Germany), 15-17 December 2014, beautifully organized by Eckhard Wolf and Pascale Chavatte-Palmer, Chair and Co-Chair of this EU-COST Action BM1308. This conference, open to any interested researcher in the field, represented the official launch of the SALAAM project, to discuss about the role of large animal models in Translational Medicine, “Bridging the Gap between Basic and Clinical Research”, as indicated in the SALAAM logo. During these three days, about 120 scientists, including researchers not initially associated with SALAAM (including several ISTT members), gathered at the Gene Center, LMU Munich, to share their views about the role of large animal models in biomedicine.
The meeting started with a welcome address by Eckhard Wolf (LMU, Munich, Chair of SALAAM) who set the stage and underlined the need to use appropriate animal models for succeeding in translational research. In the past, large amount of resources have been devoted to rodents, mostly mice, in biomedicine, where mouse models have become instrumental for the current understanding of how most of our genes work and greatly facilitated the progress in the post-genomic era. However, in spite of mice being widely used in Biomedicine to model human diseases, often mice fail to accurately reproduce the features associated with a given human pathology. Therefore there is an urgent need to develop non-rodent animal models that would mimic aspects of human anatomy and human physiology more closely. Pigs, small ruminants and rabbits appear to be excellent candidates to follow up the preliminary discoveries made in mice, and they are the main purpose of the SALAAM initiative, through all the appointed participants, experts in these large animal models. The conference continued for its first day with lectures by A. Aartsma-Rus (NL), and S. Wildhirt (DE), who described examples of use of large animal models for Duchenne muscular dystrophy and for the development of medical devices, respectively. The initial Ethical perspective on the use of large animals was provided by N. Stingelin (CH). This first day concluded with an interesting key-note lecture by M.M. Mohiuddin (USA) on the recent advances in pig-to-primate cardiac xenotransplantation.
On the second day, the conference presented the very large repertoire of methods and techniques that are currently available for Genetic Tailoring of large animal models. Angelika Schnieke (DE) introduced the state of art for the current genetic engineering of large animals, nicely summarizing many years of techniques and developments that have been successfully applied for the production of large genetically modified animal models. This initial talk was followed by a presentation by Lluis Montoliu (ES) on the use of CRISPR-Cas9 approaches to functionally analyze the role of non-coding genomic sequences, illustrated with some examples tested in mice, depicting the important role of rodents in proof-of-concept type of experiments, before undertaking subsequent experiments in larger animal models. B. Grzeskowiak (PL) presented an innovative set of nanomagnetic gene delivery vectors for transgenesis. Two additional talks illustrated the power of genetic engineering of the pig genome, using transposons (W.A. Kues, DE) or very elaborated gene cassettes for regulating and tracing disease genes (J.E. Jakobsen, DK). The session ended with a presentation from goats, where L. Boulanger (FR) reported the role of FOXL2 as a female sex-determining gene.
The SALAAM conference continued with a session devoted to systematic phenotyping initiatives of large animal models. At first, H. Fuchs (DE), presented the experience and phenotyping pipeline of the German Mouse Clinic, operating within the Infrafrontier consortium, and a good example of successful systematic phenotyping in mice. Next, Pascale Chavatte-Palmer (FR) discussed the achievements and challenges of imaging techniques in large animal models, through her studies on reproduction and fetal development. J. Tibau (ES) presented his interesting studies using pigs to analyze human obesity and to validate the effect of diets on the evolution of fat deposition using tomography approaches. A. Blutke (DE) introduced the impressive Munich MIDY-PIG Biobank initiative, as a unique resource for translational diabetes research. The two last talks presented the use of pigs as models for respiratory infections (K. Skovgaard, DK) or cystic fibrosis (I. Caballero, FR).
The last standard session of this SALAAM conference was devoted to discuss how to select the best animal model. This session began with an interesting presentation by J. Langermans (NL), who shared their initiative of non-human primate biobanking for translational medicine, a collaborative consortium where most of the nonhuman primate research centres in Europe were represented. He also discussed the unique features of non-human primates to investigate devastating diseases affecting us, such as the new infections (i.e. Ebola) or neurodegenerative diseases (i.e. Alzheimer, Parkinson) , often very challenging to be reproduced in non-primate animal models. Next, Antonio Gonzalez-Bulnes (ES) discussed the advantages and challenges of using pigs and sheep animal models, whereas L. Hiripi (HU) presented the unique features of the rabbit models. V. Huygelen (BE) discussed the use of piglets to investigate the human low birth weight cases , and A. Navarrete Santos (DE) further presented rabbits as ideal models for investigating diabetes during pregnancy. Diabetes research was also the focus of the last speaker of the session, G. Pennarossa (IT), whose experimental dessigns are focused on the use of dogs to explore cell therapy-based treatments.
The SALAAM first public conference ended with an excellent and very motivating talk by Karin Blumer (CH) on the ethical aspects of using large animals. She challenged the audience with the question whether “size did matter?” when it comes to Ethics and Animal Models. Her presentation nicely illustrated the different Ethical perspectives existing in the field and, most importantly, the relevant parameters that should be taken into account in order to properly address this question. She presented the “size” of an animal as an accidental attribute, not an intrinsic value, that must not determine its moral status. This presentation triggered an interesting and live discussion among the participants.
On the third and last day, the different working groups of SALAAM gathered first independently to discuss the next initiatives and eventually shared their conclusions in a combined general session. The planned initiatives will include the organization of practical workshops on CRISPR-Cas9 and transposon technologies, the generation of specific pig Cre-transgenic lines for the production of conditional pig mutant animal models, the need to standardize phenotyping protocols associated with additional specific training courses, the preparation of biobanks and associated databases for archiving and sharing tissues from large animal models, and the creation of a group to analyze the implementation of the 2010/63/EU Directive across Europe, the public perception and ethical issues of animal research, and the need for training to adequately communicate results to the public.
Information about future plans, initiatives and activities of the SALAAM EU-COST action will be available from its dedicated web site.
Happy New Year to all ISTT Members!. Here, you can download a free copy of the 2015 ISTT Calendar. This edition has been nicely prepared by ISTT Board Member Karen Brennan (Sydney, Australia), using numerous beautiful images generously provided by members and supporting companies. Download it, print it and use it!. Enjoy it!.
The most popular ISTT meeting held to date took place last week in Edinburgh, UK, at the Assembly Rooms. More than 530 participants gathered in Scotland for the 12th Transgenic Technology (TT2014) meeting during three days, 6 to 8 October 2014, to discuss the latest advances in methods and applications for generating and analyzing genetically modified animals. The local Organizers, Douglas Strathdee, Peter Hohenstein and Bruce Whitelaw showed us how to run an splendid TT meeting Scottish style. The Organizing committee, helped by the In-Conference team and the ISTT council and Administration, should be praised for putting together an excellent collection of talks, covering the most up-to-date topics, where all participants could learn and share their experiences.
As many as 54 speakers were invited to present their research, including two keynote addresses (Rudolf Jaenisch, Alexandra Joyner), at the opening and clossing of the TT2014 meeting, two ISTT awarded scientists (Janet Rossant-10th ISTT Prize- and Feng Zhang-3rd ISTT Young Investigator Award), 26 invited speakers, 6 Showcase presentations from Scottish scientists, 5 short talks and 15 teasers selected from Poster abstracts. The impressive numbers of the TT2014 meeting continue with 176 Posters presented by participants attending the conference in Edinburgh and the many sponsors and exhibitors that generously contributed to the success of the 12th Transgenic Technology Meeting. The ISTT conference was followed by a hands-on workshop on basic zebrafish transgenic methods.
During the TT2014 meeting, at the corresponding ISTT General Assembly, the ISTT Members approved to dissolve the legal entity representing the Society in Spain, which has been substituted by the new legal entity, ISTT, Inc., a not-for-profit association registered in the New York State (USA) that from now onwards will be representing the interests of the Society. Also, during the course of the ISTT conference in Edinburgh, the ISTT Board members awarded Lluis Montoliu (Founder and Past-President of the ISTT, 2006-2014) and thanked his dedicated work for the ISTT, since its inception. Jan Parker-Thornburg is the new President of the ISTT.
The conference in Edinburgh concluded with the warm invitation by Radislav Sedlacek (IMG, Prague, Czech Republic), Organizer of the 13th Transgenic Technology Meeting, TT2016, to attend the next ISTT conference that will be held in Prague, Czech Republic, on 20-23 March 2016.
Good bye and thanks to Edinburgh! Hello and see you all again in Prague!
The 12th Transgenic Technology Meeting is about to begin this forthcoming weekend. On Sunday, 5 October, the Organizers have nicely prepared a welcome pre-meeting dinner to get together and meet all colleagues attending. The real TT2014 meeting‘s kick off will be on Monday morning, 6 October. During the following three days all delegates will have the pleasure (and the privilege, owing the great interest triggered by this conference, absolutely sold out) to listen and discuss the latest advances in transgenic technologies, through lectures delivered by the key players in our field, the ones that have developed or contributed to disseminate the use of the newest tools, the most updated experimental strategies applied to generate and analyze genetically modified animals. More than 530 participants will fill the Assembly Rooms in the historic city of Edinburgh. This TT meeting has become not only the most popular ISTT conference organized to date but also the TT meeting where the highest number of posters (176) will be shown. Therefore, besides enjoying the talks, all TT2014 delegates will have a unique opportunity to browse through the work of dozens of many other laboratories and facilities, willing to share their advances, problems encountered, solutions found and innovative proposals.
The International Society for Transgenic Technologies (ISTT) is proud to have chosen Edinburgh as the venue for TT2014 and, hence, wants to congratulate the Organizing Team, led by Douglas Strathdee, Chair of the conference, along with Peter Hohenstein and Bruce Whitelaw, co-chairs, the technical secretariat provided by In-Conference and the rest of members of the Organizing committees, for having prepared what surely will be another great TT meeting, as all precedent meetings were. The TT2014 meeting will be followed by a practical workshop on Zebrafish Transgenic Techniques, where a limited number of participants will have the opportunity to meet experts in the field and learn the basic techniques applied nowadays to use this vertebrate as an alternative animal model to study gene function or disease.
If you are already in Edinburgh, enjoy the city! If you are travelling to Edinburgh: have a safe trip! If, however, and unfortunately, you have not managed to attend this time, but you are a member of the ISTT, please wait to grasp some of the excellence and talent that will be presented during next week through the talks that we will be at the members-only area, after obtaining the consent from the corresponding speakers. Also, life goes on, and ISTT is already planning for the next TT meeting, already launched: the 13th Transgenic Technology Meeting (TT2016) that will be held in Prague (Czech Republic) in March 2016, organized by Radislav Sedlacek.
The International Society for Transgenic Technologies (ISTT) will soon move its headquarters from Europe to America, from Spain (Europe Union) to the State of New York (United States of America). After the 12th Transgenic Technology (TT) meeting in Edinburgh, TT2014, the ISTT Society will be legally represented by a new non-profit entity: ISTT, Inc., registered in the State of New York (USA) in May 2013, after the corresponding approval was obtained from ISTT members at the Extraordinary General Assembly held at the TT2013 meeting, in Guangzhou, China, in February 2013. This moving process was essentially undertaken to allow any member to run for any position at the Board and to reduce tax running costs. The process is meant to be smooth and transparent to all members which will be kindly requested to join the new entity, to approve the new bylaws and to approve the new Board. Everything else will remain the same and the ISTT members will continue enjoying the same benefits from being part of the ISTT Society. The ISTT thank all of its members for their support and collaboration.