TT2013 meeting report published in Transgenic Research

TT2013 meeting report published in Transgenic Research
TT2013 meeting report published in Transgenic Research

The TT2013 meeting report, written by Douglas Strathdee (Beatson Institute for Cancer Research, Glasgow, Scotland, UK) and C. Bruce A. Whitelaw (Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, Scotland, UK) has just been published, online, at the Transgenic Research journal web site. This review, entitled ‘TT2013 meeting report: the Transgenic Technology meeting visits Asia for the first time‘ nicely summarizes the talks and activities held during the recent 11th Transgenic Technology meeting, held in Guangzhou (China), on February 25-27, 2013, along with the subsequent hands-on workshop that was organized, on February 28-March 2, 2013. Douglas and Bruce, together with Peter Hohenstein (Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, Scotland, UK) are the Organizers of the next 12th Transgenic Technology meeting, TT2014, which will be held in Edinburgh (Scotland, UK) on October 6-8, 2014.

First transgenic sheep made in SouthAmerica announced in Uruguay by ISTT members

Members of the team at IRAUy, led by A. Menchaca, and collaborators from Inst. Pasteur, led by M. Crispo, are holding several baby lambs (Photo by J. Calvelo)
Members of the team at IRAUy, led by A. Menchaca, and collaborators from Inst. Pasteur, led by M. Crispo, are holding several baby lambs (Photo by J. Calvelo)

Researchers at the Institute of Animal Reproduction in Uruguay (IRAUy), led by Alejo Menchaca (ISTT Member), in collaboration with members of the Transgenic and Experimental Animal Unit (UATE) of the Institut Pasteur de Montevideo, led by Martina Crispo (ISTT Member) and Ignacio Anegon‘s laboratory (ISTT Member), of the Transgenic Rats common facility, ITERT, INSERM, Nantes, France, working in Europe but born in Uruguay, have announced the generation of several green transgenic sheep made with lentiviruses carrying a GFP reporter transgene. These green animals represent the first transgenic sheep produced in Uruguay, and in SouthAmerica. According to the press release and the authors of this biotechnological project, up to nine transgenic sheep were generated last year, 6 months ago, at the IRAUy, after 2 years of work.

Green (GFP) transgenic sheep generated in Uruguay through a scientific collaboration involving the teams of Alejo Menchaca, Martina Crispo and Ignacio Anegon (Photo by J. Calvelo)
Green (GFP) transgenic sheep generated in Uruguay through a scientific collaboration involving the teams of Alejo Menchaca, Martina Crispo and Ignacio Anegon (Photo by J. Calvelo)

This proof-of-concept experiment demonstrates the technological skills and capacity of these teams and institutions in Uruguay, who have been able to produce these first transgenic lambs, and hence, they must be praised by their achievement. In the future, additional genetically modified livestock will be created, aiming to produce recombinant proteins of biomedical or industrial interest in the milk of these transgenic animals, following similar experiments already carried out in other countries. The International Society for Transgenic Technologies (ISTT) is proud to count among its members these three excellent researchers and wishes to congratulate them for their success in their experiments.

First GFP transgenic sheep produced in Uruguay and SouthAmerica (Photo by J. Calvelo)
First GFP transgenic sheep produced in Uruguay and SouthAmerica (Photo by J. Calvelo)

The most immediate precedents for genetically modified livestock in SouthAmerica include transgenic goats generated in 2009 by the team of Vicente Freitas (ISTT Member) at the State University of CearĂ¡, Fortaleza (Brazil), expressing hG-CSF in their milk, and several transgenic cows generated by a biotech firm, Biosidus, and by INTA, in Argentina, in 2008 and 2011, respectively, producing therapeutical proteins in their milk.

ISTT will be present at the FELASA-2013 Congress in Barcelona

ISTT will be present at the FELASA-2013 Congress in Barcelona
ISTT will be present at the FELASA-2013 Congress in Barcelona

The International Society for Transgenic Technologies (ISTT) will be present, as exhibitor, at the FELASA-2013 Congress that will be held in Barcelona (Spain), on 10-13 June 2013. The ISTT had already supported and participated as co-sponsor in previous FELASA meetings, but this time our Society will be represented officially by Alison Cameron, the ISTT administrative assistant, who will be responsible for the ISTT booth (#230) at the FELASA-2013 congress venue. We warmly invite all ISTT members attending the FELASA-2013 meeting to visit us at the ISTT booth.