Poster of the TT2010 meeting

Official Poster of the TT2010 Meeting
Official Poster of the TT2010 Meeting

The official Poster of the TT2010 meeting, to be held in Berlin (Germany) on March 22-24, 2010, has just been released. The poster includes currently available information regarding invited speakers who confirmed their attendance and the list of topics that will be covered during the conference. Additional information can be obtained directly from the official TT2010 meeting web site, at www.tt2010.org.

Nantes 2009: meeting report

Nantes meeting on Transgenic Animals
Nantes meeting on Transgenic Animals

On June 8 2009 was held in Nantes, France, the international meeting “Transgenesis ; recent technical developments and applications”. This meeting is the second one of its kind to be organized by the Transgenic Rats Nantes facility from the INSERM UMR 643 and Biogenouest. The meeting was supported by several academic institutions, as well as private companies. The meeting received support and co-sponsorship from the International Society for Transgenic Technology (ISTT). Around 100 participants, from France but also in significant proportion from different European countries and Canada, attended the meeting and registration prices were kept as low as possible to facilitate the participation of students.

The meeting aimed to provide an update on recent technical developments in the generation of transgenic animals and in some of their applications. It was intended for Master, PhD and medical students with a background in molecular biology and genetics as an introduction to future work in these rapidly developing areas of research. It was also intended for post-docs and scientists already working in certain of these fields and who are interested in expanding their knowledge on the potential applications of these new techniques to their models. Here, you can download the corresponding meeting report.

Promoting sharing and archiving of mice

A genetically-modified mouse generated for research purposes (LM)
A genetically-modified mouse generated for research purposes (LM)

Nature published yesterday an interesting Editorial promoting the concept of sharing and archiving mouse models that are constantly generated world wide, as a way to adequately trigger our progress in science more efficiently, to avoid repeated experiments and duplication of efforts, and to allow different laboratories to use the same research tools and animal models.

These ideas were discussed in a recent meeting on “Data Sharing in Mouse Functional Genomics“, held in Rome in May 20-22, 2009, within the European Project CASIMIR, a coordination action of the 6th Framework Programme of the European Commission, that focus on co-ordination and integration of databases set up in support of FP5 and FP6 projects containing experimental data, including sequences, and material resources such as biological collections, relevant to the use of the mouse as a model organism for human disease.

Archiving of genetically-modified and, in general, mutant mice can be done using any of the existing international platforms, such as: EMMA, The Jackson Laboratory, MMRRC, MMHCC, Riken-RBRC, Riken-CARD, CMC, CMMR, Australian Phenomics Network, etc…. all coordinated and available through the Federation of International Mouse Resources (FIMRE) and with all their mouse repository contents searchable through the International Mouse Strain Resource (IMSR).

In order to promote sharing and archiving of all new mice that are produced the Editorial of Nature recommends that “Journals should now require researchers to place their mice in repositories as a condition of publication. And funding agencies should require repository plans to be included in all grant applications that are likely to generate new mouse strains. Part of the grant money should be reserved for this task and final reports or evaluations of the grants should refer to the repository used. The repositories themselves should help the journals and funding agencies by finding a way to generate a unique accession number for each mouse strain.”

Transgenesis meeting in Nantes, France

Ignacio Anegon (left, Chair) and Louis-Marie Houdebine (invited speaker)
Ignacio Anegon (left, Chair) and Louis-Marie Houdebine (invited speaker)

The 1-day meeting on “Transgenesis: recent technical developments and applications“, organized by Ignacio Anegon and Séverine Menoret, from the Transgenic Rats Common Facility of IFR 26 and Ouest-Genopole, University of Nantes) was successfully held on June 8, 2009 in Nantes, France. This meeting was co-sponsored by the International Society for Transgenic Technologies (ISTT).

Séverine Menoret (right) and her colleagues from the local organizing committee
Séverine Menoret (right) and her colleagues from the local organizing committee

Invited speakers included: Michel Cohen-Tannoudji, Louis-Marie Houdebine, Kader Thiam, Toni Cathonen, Roland Buelow, Daniel Bujard, Edwin Cuppen, Cesare Galli, Lluis Montoliu, Marie Malissen, Jean-Louis Guenet and Laurent Lescadron. The meeting reviewed several topics in animal transgenesis, such as: animal models in biomedical research (immune system, neurodegenerative diseases), generation of the first knock-out rats, use of interference RNA, Zinc-finger nucleases, artificial chromosome-type transgenes, lentiviral vectors, ENU mutagenesis, rodents genome and transgenesis in non-mammalian vertebrates.

NorIMM meeting in Finland: Mouse as a Model Organism – From Animals to Cells

NorIMM meeting: Mouse as a Model Organism - From Animals to Cells
NorIMM meeting: Mouse as a Model Organism – From Animals to Cells

NorIMM is a Nordic network for communication between the current infrastructures for generation and phenotyping of genetically modified mice in Denmark, Finland, Norway, and Sweden. This interesting Scandinavian initiative, directed by Taina Pihlajaniemi (Institute of Biomedicine, University of Oulu, Finland), organised last week a meeting on “Mouse as a model organism – From animals to cells” (Rovaniemi and Oulu, Finland, June 2-6, 2009). The head of the Meeting Organizing Committee was Raija Soininen (Biocenter, University of Oulu), a member of ISTT.

NorIMM
NorIMM
The aim of the conference “Mouse as a model organism – from animals to cells”, was to provide first-hand information about the latest developments in the technology in generation and analysis of mouse models, and present the students and other researchers an opportunity to meet the experts. The meeting program included two parts. First, a 2,5-day symposium on June 2-4, 2009 in Rovaniemi with talks by invited speakers and a poster session with short oral presentations. The second part was a Summer school organized in Oulu on June 5-6, 2009 with lectures, group discussions, short talks by students, and demonstrations in Biocenter Oulu core facilities. Invited speakers included: Martin Hrabé de Angelis, Kari Alitalo, Andras Nagy, Lluís Montoliu, Francis Stewart, Bill Skarnes, Cory Brayton, Paul Schofield, Janan T. Epig, John Hancock, Valerie Gailus-Durner, Donald McDonald, Agnes Noël, Olivier de Wever, Sandra McAllister and Rolf Reed.
Finish landscape. Image taken from a plane taking off in Rovaniemi (Lluis Montoliu)
Finish landscape. Image taken from a plane taking off in Rovaniemi (Lluis Montoliu)