“Transgenic list” (tg-l) is now the official list of ISTT

transgenic-list (tg-l)

ISTT

The transgenic-list (tg-l), the reference channel of discussions on scientific and technical issues related to the generation and analysis of transgenic animals and transgenic research in general, established in its current format since July 1996 by Peter Sobieszczuk, has become the official list of the International Society for Transgenic Technologies (ISTT).

To illustrate this agreement, established between Peter Sobieszczuk (as the tg-list owner and therefore responsible person of the list) and Lluis Montoliu (as President of the ISTT) the ISTT will recommend and promote the use of tg-list to discuss any topic related with transgenic research. Likewise, the tg-list will announce this agreement in all messages, with a link to the ISTT WEB site.

TT2008 Meeting updated program

TT2008 Meeting

The TT2008 Meeting program has been updated, now including a session on basic techniques, inmediately before the classical round-table discussion on “Running a transgenic unit”. Please check the TT2008 Meeting WEB site for latest announcements.

Topics that will be covered in this “Basic techniques” new session include: Embryo transfer, vasectomy and ceasarean section, ES cell culture and derivation, Pronuclear and blastocyst injection and Artificial chromosome-type transgenes.

Important deadlines for the TT2008 meeting are:

Early registration: July 1, 2008
Tetraploid aggregation course and MGI workshop: August 1, 2008
Abstract submission: July 20, 2008
Last registration: September 1, 2008. Registrations will not be accepted after this date
Niagara tour and pre-conference dinner: September 1, 2008

In addition, the ISTT sponsors up to six travel awards for ISTT Members willing to attend the TT2008 meeting. Deadline for submitting an application for these travel awards is: July 1, 2008

Patents in ES cell work

mouse ES cells

Recently, at the tg-list, it was discussed the issue of patents that apply in the standard ES cell work. Those patents include the usual positive-negative selection and the use of isogenic DNA. Of course, there are many more with modifications or alternative methodologies but I believe these two methodology are still the basic ones.

According to the United States Patent and Trademark Office, these are the patents alive and active:

Positive-negative selection methods and vectors
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 5,464,764
Issued: November 7, 1995
Filed: February 4, 1993
Assignee: University of Utah Research Foundation (Salt Lake City, UT)

Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 5,487,992
Issued: January 30, 1996
Filed: June 28, 1993
Assignee: University of Utah Research Foundation (Salt Lake City, UT)

Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 5,627,059
Issued: May 6, 1997
Filed: June 5, 1995
Assignee: University of Utah (Salt Lake City, UT)

Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 5,631,153
Issued: May 20, 1997
Filed: June 5, 1995
Assignee: University of Utah (Salt Lake City, UT)

Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 6,204,061
Issued: March 20, 2001
Filed: January 9, 1997
Assignee: University of Utah Research Foundation (Salt Lake City, UT)

Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
Capecchi; Mario R., Thomas; Kirk R.
US Patent: 6,204,061
Issued: February 10, 2004
Filed: November 28, 2000
Assignee: University of Utah Research Foundation (Salt Lake City, UT)

Gene targeting in animal cells using isogenic DNA constructs
Berns; Anton, Robanus Maandag; Els, te Riele; Hein
US Patent: 5,789,215
Issued: August 4, 1998
Filed: August 7, 1997
Assignee: GenPharm International (San Jose, CA)

High efficiency gene targeting in mouse embryonic stem cells
Berns; Anton, Robanus Maandag; Els, te Riele; Hein
US Patent: 6,653,113
Issued: November 25, 2003
Filed: February 19, 1999
Assignee: Genpharm International, Inc. (Mountain View, CA)

ISTT Chat Session on “Sperm cryopreservation and IVF techniques”

Julia Fernandez working at the CNB cryopreservation lab

On Tuesday, April 15th, 2008 the International Society for Transgenic Technologies (ISTT) will sponsor an interactive chat session about “Sperm Cryopreservation and IVF techniques

Confirmed expert panelists are (updated April 9, 2008):

Jorge M. Sztein DVM, Ph.D.
Director, Colony Management and Research Support
Genetic Engineering Core Facility
National Eye Institute
National Institutes of Health
Bethesda, MD, USA

Martin D Fray, PhD
Frozen Embryo and Sperm Archive – manager
MRC Mammalian Genetics Unit
Harwell
Didcot
Oxfordshire, UK

G. Charles Ostermeier, Ph.D.
Associate Research Scientist
Reproductive Technology Specialist
The Jackson Laboratory
Technology Evaluation and Development
Reproductive Sciences
Bar Harbor, ME, USA

Dr. Susan Marschall
Cryo-Unit – EMMA
Institute of Experimental Genetics
Helmholtz Zentrum Muenchen
German Research Center for Environmental Health (GmbH)
Neuherberg, Germany

Carlisle P. Landel, Ph.D.
Director, Transgenic and Gene Targeting Facility
Kimmel Cancer Center
Thomas Jefferson University
Philadelphia, PA, USA

Auke Boersma, Ph.D.
Veterinarian
Cryobiology / Institute of Experimental Genetics
European Mouse Mutant Archive – EMMA
Neuherberg, Germany

The chat sesssion will take place at the following time-table:

23:00 Athens
22:00 Madrid, Rome, Paris, Berlin, Munich, Stockholm
21:00 London, Lisboa
17:00 Sao Paulo
16:00 Toronto, New York, Philadelphia, Bethesda, Bar Harbor (US East Coast)
15:00 Houston, Chicago
14:00 Denver
13:00 Los Angeles, California (US West Coast)
10:00 Honolulu
01:30 New Delhi, on next day: April 16st
04:00 Perth, on next day: April 16st
05:00 Tokyo, on next day: April 16st
06:00 Melbourne, on next day: April 16st
07:00 Brisbane, on next day: April 16st
08:00 Auckland, on next day: April 16st

You can check in this WEB for additional meeting times across the world.

If you are not already an ISTT Member, you can join the ISTT to participate in the CHAT session.